Key result
Accessory pathway ablation induces terminal QRS vector changes in ~100% of patients.
Why the study?
Does ablation of a single accessory pathway alter the terminal QRS vector in patients with preexcitation syndrome?
Observational (n=30)
Does ablation of a single accessory pathway alter the terminal QRS vector in patients with preexcitation syndrome?
Spatial vectorcardiography demonstrates that preexcitation syndrome affects both initial and terminal QRS vectors, aiding in the diagnosis of atypical preexcitation and localization of accessory pathways.
Answers are grounded in this paper and cite their sources.
Post-ablation terminal QRS vector changes may aid accessory pathway localization; hypothesis-generating in small cohort, requires prospective validation.
BACKGROUND: Preexcitation syndrome could affect terminal QRS vector, which is not emphasized in clinic. In this study, we made a comparison between vectorcardiogram (VCG) before and after ablation to observe the change of terminal QRS vector. Furthermore, the relationship between the change of terminal QRS vector and accessory pathway (AP) as well as the change of initial QRS vector (delta vector) was analyzed. METHODS: Thirty patients who were proved to have a single AP by ablation were included. All patients were divided into seven groups based on the AP location. Comparison between VCG before and after ablation was made to observe the change of terminal and delta vector. The relationship between the change of terminal QRS vector and AP location as well as delta vector was analyzed. RESULTS: (1) All 30 patients had a change in terminal QRS vector (elevation and/or azimuth) in comparison to postablation VCG. (2) The change of terminal QRS vector was related to delta vector and AP location. The agreement and consistency between the change of terminal QRS vector and delta vector were 91.65% and 0.856 (P < 0.01), respectively. CONCLUSIONS: (1) Both initial and terminal QRS vector are affected by the antegrade conduction of AP. The change of terminal QRS vector is related to the AP location and delta vector. (2) The effect of preexcitation syndrome on QRS terminal vector is shown as more intuitive and easy in spatial vector by comparison with electrocardiogram, which is helpful for the diagnosis of atypical preexcitation and localization of AP.
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Wang et al. (2016) conducted an observational in Preexcitation syndrome (n=30). Radiofrequency catheter ablation vs. Pre-ablation baseline was evaluated on Change in terminal QRS vector (elevation and/or azimuth) after ablation (p=<0.01). Ablation of a single accessory pathway resulted in terminal QRS vector changes in 100% of patients, with terminal vector changes showing 91.65% agreement with initial delta vector changes.
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