Key result
Diastolic heart failure, characterized by a normal ejection fraction (≥50%) without primary valve disease, accounts for 40% to 50% of all heart failure patients.
Highlights the growing epidemiological importance of heart failure with preserved ejection fraction (diastolic heart failure) in the aging population.
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Diastolic dysfunction underlies HFpEF; extends mechanistic insights but leaves open targeted therapies.
Margaret M. Redfield (2004) conducted a review in Diastolic heart failure. Diastolic heart failure, characterized by a normal ejection fraction (≥50%) without primary valve disease, accounts for 40% to 50% of all heart failure patients.
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