May 5, 2004New England Journal of Medicine107 citations
View Full PaperUnderstanding “Diastolic” Heart Failure
Key Result
Diastolic heart failure, characterized by a normal ejection fraction (≥50%) without primary valve disease, accounts for 40% to 50% of all heart failure patients.
Key Points
- This research aims to explore the prevalence and implications of diastolic heart failure in the elderly population. It seeks to highlight the differences between diastolic and systolic heart failure.
- Review of epidemiologic studies on heart failure prevalence in the elderly population
- Analysis of ejection fraction data in heart failure cases
- Comparison between diastolic and systolic heart failure characteristics
- 40-50% of heart failure cases have a normal ejection fraction (≥50%)
- Diastolic heart failure is prevalent despite advancements in treatment for systolic heart failure
- Basic and clinical research is evolving to better address this condition
Structured PICO
P
Population
Patients with heart failure, specifically those with normal ejection fraction (≥50 percent) without primary valve disease (commonly referred to as 'diastolic' heart failure).
Highlights the growing epidemiological importance of heart failure with preserved ejection fraction (diastolic heart failure) in the aging population.
Abstract
Heart failure is common and costly, and it primarily affects the elderly. As the elderly population expands, there will be marked increases in the number of persons with heart failure. Epidemiologic studies have established that 40 percent to 50 percent of patients with heart failure have a normal ejection fraction (≥50 percent) without primary valve disease, a clinical syndrome that is commonly referred to as “diastolic” heart failure. Despite great progress in our understanding of and therapeutic approach to heart failure associated with systolic dysfunction, or systolic heart failure, we are now realizing that basic research and clinical investigations have . . .