Key result
Onset of puberty (HR 8.01; 95% CI 3.18-20.16; p<0.001), higher HbA1c, and older age at diagnosis were significant risk factors for developing microalbuminuria in children with type 1 diabetes.
Population
955 children with type 1 diabetes mellitus diagnosed ≤16 years of age, mean age at onset 8.5 years, 462…
Design
Cohort
Follow-up
mean diabetes duration of 7.6 years
Authors
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May support puberty-timed microalbuminuria surveillance in pediatric type 1 diabetes; hypothesis-generating for HbA1c and diagnosis age.
Cohort (n=955)
Hazard Ratio: 8.01 (95% CI 3.18–20.16)
p-value: p=<0.001
Onset of puberty, higher HbA1c, and older age at diagnosis are major risk factors for developing microalbuminuria in children with type 1 diabetes.
Gallego et al. (2006) conducted a cohort in Type 1 diabetes mellitus (n=955). Onset of puberty was evaluated on Development of microalbuminuria (HR 8.01, 95% CI 3.18-20.16, p=<0.001). Onset of puberty (HR 8.01; 95% CI 3.18-20.16; p<0.001), higher HbA1c, and older age at diagnosis were significant risk factors for developing microalbuminuria in children with type 1 diabetes.
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