Key result
Four weeks of daily cold exposure increased the volume of metabolically active brown adipose tissue from 66 to 95 mL (P<0.05) and increased its oxidative capacity 2.2-fold (P<0.05).
Why the study?
Does 4 weeks of daily cold exposure increase the volume and oxidative capacity of brown adipose tissue in nonacclimated men?
Population
6 nonacclimated men
Comparison
4 weeks of daily cold exposure using a… vs Baseline (before 4 weeks of cold acclimation)
Design
Cohort
Follow-up
4 weeks
Authors
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Small study suggests cold recruits BAT in humans; hypothesis-generating, leaves open clinical translation.
Does 4 weeks of daily cold exposure increase the volume and oxidative capacity of brown adipose tissue in nonacclimated men?
Effect estimate: 45% increase
Absolute Event Rate: 95% vs 66%
p-value: p=< .05
Four weeks of daily cold exposure increases the volume and oxidative capacity of metabolically active brown adipose tissue in humans, enhancing its contribution to cold-induced thermogenesis.
Blondin et al. (2014) studied this question. Daily cold exposure vs. Baseline (before acclimation) was evaluated on Brown adipose tissue (BAT) volume of activity (mL) (45% increase, p=< .05). Four weeks of daily cold exposure increased the volume of metabolically active brown adipose tissue from 66 to 95 mL (P<0.05) and increased its oxidative capacity 2.2-fold (P<0.05).
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