Key result
Fluoxetine therapy (20 mg/day) was associated with QTc prolongation (478 msec) and recurrent torsades de pointes in an 83-year-old woman, which resolved upon discontinuation.
Why the study?
Does fluoxetine cause QTc prolongation and torsades de pointes in an elderly patient?
Population
83-year-old woman presenting with transient unexplained loss of consciousness, left bundle branch block, and…
Design
Case_report
Follow-up
8 months
Authors
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May warrant QTc monitoring with fluoxetine in elderly patients; single case leaves risk magnitude open.
Case Report (n=1)
Does fluoxetine cause QTc prolongation and torsades de pointes in an elderly patient?
Fluoxetine can induce QTc prolongation and torsades de pointes, which resolves upon discontinuation of the medication.
Wilting et al. (2006) conducted a case report in QTc prolongation and torsades de pointes (n=1). Fluoxetine was evaluated on QTc prolongation and torsades de pointes. Fluoxetine therapy (20 mg/day) was associated with QTc prolongation (478 msec) and recurrent torsades de pointes in an 83-year-old woman, which resolved upon discontinuation.
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