Key result
Transvenous lead extraction achieves comparable procedural success in octogenarians versus younger patients.
Why the study?
Managing elderly patients with CIED infection or malfunction may be challenging, and data on the safety and effectiveness of transvenous lead extraction in Chinese octogenarians are needed.
Does transvenous lead extraction have similar efficacy and safety in octogenarian patients compared to younger patients?
Cohort (n=1,106)
No
Does transvenous lead extraction have similar efficacy and safety in octogenarian patients compared to younger patients?
Absolute Event Rate: 96.7% vs 95.3%
p-value: p=0.39
Supports TLE consideration in octogenarians without added procedural risk; observational data leaves open need for prospective validation.
BACKGROUND: Managing elderly patients with infection or malfunction deriving from a cardiac implantable electronic device (CIED) may be challenging. We report the safety and effectiveness of transvenous lead extraction in Chinese octogenarian patients. HYPOTHESIS: Transvenous lead extraction can be performed safely and successfully in the Chinese octogenarians. METHODS: We retrospectively identified all patients who underwent TLE at our institution between March 2013 and January 2021. This population was divided into the following two groups based solely on age: octogenarians and non-octogenarians. These two groups were compared on the basis of several characteristics and clinical outcomes. RESULTS: Consecutive 1106 patients were analyzed, including 184 (16.6%) octogenarians and 922(83.4%) non-octogenarians. The octogenarians presented more comorbidities. A total of 378 leads and 2004 leads were removed from the patients in the octogenarian group and non-octogenarian group, respectively. The mean lead implant duration was 6.1 ± 5.1 and 5.8 ± 4.6 years for octogenarians and non-octogenarians (p = 0.296). The majority of the patients in both groups underwent TLE through the femoral approach (67.5% vs 61.6%, p = 0.14). The complete procedure success rate was similar between the octogenarian and non-octogenarian group (96.7% vs.95.3%, p = 0.39). There were no differences with respect to the proportion of minor, major complications and deaths. Long-term mortality (median time 3.3 years) after TLE in octogenarians was significantly higher compared with younger individuals. CONCLUSIONS: At experienced centers, transvenous lead extraction can be performed safely in Chinese octogenarians with procedural success rate and complication rate comparable to younger individuals.
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Zhou et al. (2021) conducted a cohort in Cardiac implantable electronic device (CIED) infection or malfunction (n=1,106). Age ≥ 80 years (octogenarians) vs. Age < 80 years (non-octogenarians) was evaluated on Complete procedural success (p=0.39). In a cohort of 1,106 Chinese patients undergoing transvenous lead extraction, octogenarians had a comparable complete procedural success rate to younger patients (96.7% vs. 95.3%, p=0.39).
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