Key result
BAV models show ~6-fold higher turbulent kinetic energy and increased wall shear stress versus TAV.
Why the study?
Aortic valve disorders can cause turbulent transitions in aortic blood flow, and understanding turbulence is crucial for foreseeing how the disease will progress.
Does a bicuspid aortic valve configuration alter blood flow patterns and turbulence compared to a tricuspid aortic valve in computational models?
Does a bicuspid aortic valve configuration alter blood flow patterns and turbulence compared to a tricuspid aortic valve in computational models?
Large eddy simulations demonstrate that bicuspid aortic valves induce asymmetric flow, higher turbulent kinetic energy, and increased wall shear stress in the ascending aorta compared to tricuspid valves.
Aortic valves with bicuspids have two rather than three leaflets, which is a congenital heart condition. About 0.5-2% of people have a bicuspid aortic valve. Blood flow through the aorta is commonly believed to be laminar, although aortic valve disorders can cause turbulent transitions. Understanding the impact of turbulence is crucial for foreseeing how the disease will progress. The study's objective was use large eddy simulation to provide a thorough analysis of the turbulence in bicuspid aortic valve dysfunction. Using a large eddy simulation, the blood flow patterns of the bicuspid and tricuspid aortic valves were compared, and significant discrepancies were found. The velocity field in flow in bicuspid configurations was asymmetrically distributed toward the ascending aorta. In tricuspid aortic valve (TAV) the flow, on the other hand, was symmetrical within the same aortic segment. Moreover, we looked into standard deviation, Q-criterion, viscosity ratio and wall shear stresses for each cases to understand transition to turbulence. Our findings indicate that in the bicuspid aortic valve (BAV) case, the fluid-dynamic abnormalities increase. The global turbulent kinetic energy and time-averaged wall shear stress for the TAV and BAV scenarios were also examined. We discovered that the global turbulent kinetic energy was higher in the BAV case compared to TAV, in addition to the increased wall shear stress induced by the BAV in the ascending aorta.
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Kara et al. (2023) studied Bicuspid aortic valve (n=2). Bicuspid aortic valve vs. Tricuspid aortic valve was evaluated on Maximum Global Turbulent Kinetic Energy (GTKE) in cm2/s2. The bicuspid aortic valve model demonstrated a substantially higher maximum global turbulent kinetic energy (3177.6 vs 548.5 cm2/s2) and increased wall shear stress compared to the tricuspid model.
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