Why the study?
Does bicuspid aortic valve geometry alter ascending aortic fluid dynamics compared to tricuspid geometry?
Population
Numerical simulation models of ascending aorta hemodynamics
Comparison
Bicuspid aortic valve configurations vs Tricuspid aortic valve configuration
Design
Preclinical
Authors
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BAV flow changes may contribute to aortopathy; leaves open clinical relevance pending human validation.
Does bicuspid aortic valve geometry alter ascending aortic fluid dynamics compared to tricuspid geometry?
Computational simulations show that bicuspid aortic valve geometry increases wall shear stress and flow asymmetry in the ascending aorta, supporting a hemodynamic mechanism for aneurysm formation.
Vergara et al. (2011) studied this question.
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