Five-year Clinical and Economic Outcomes Among Patients With Medically Managed Severe Aortic Stenosis
Key result
Medical management of severe aortic stenosis in elderly patients resulted in an 88.4% overall mortality rate over 5 years and total costs of $63,844 per patient.
Why the study?
What are the long-term clinical and economic outcomes of elderly patients with severe aortic stenosis undergoing medical management?
Population
2150 Medicare patients with severe aortic stenosis and a recent hospitalization for heart failure, who did…
Design
Cohort
Follow-up
5 years
Authors
Discussion
Loading...
Member takes
Implication
High mortality and costs with medical management in elderly severe AS warrant individualized decisions; leaves open optimal strategies in contemporary cohorts.
Study Design
Type
Cohort (n=2,150)
Multicenter
Yes
Structured PICO
What are the long-term clinical and economic outcomes of elderly patients with severe aortic stenosis undergoing medical management?
P
Population
2,150 elderly patients (mean age 82, 64% female) with severe aortic stenosis and recent heart failure hospitalization managed medically, followed for 5 years.
E
Exposure
Medical management (no valve replacement surgery)
O
Outcome
Overall mortality, medical resource use, and costs over 5 yearshard clinical
Elderly patients with severe aortic stenosis managed medically have very poor survival (88.4% mortality at 5 years) and incur substantial healthcare costs, highlighting the need for cost-effective interventions like TAVR.
Cite This Study
Clark et al. (2012) conducted a cohort in severe aortic stenosis (n=2,150). Medical management was evaluated on overall mortality. Medical management of severe aortic stenosis in elderly patients resulted in an 88.4% overall mortality rate over 5 years and total costs of $63,844 per patient.