Key result
A history of cardiovascular disease in patients with dementia was associated with higher 3-year mortality and increased readmission risk compared to those without a history of CVD.
Why the study?
The study was conducted to evaluate the impact of cardiovascular disease on mortality and readmission risk in patients with dementia.
Does a history of cardiovascular disease increase mortality and hospital readmission risk in patients with dementia?
Cohort (n=59,194)
Yes
Does a history of cardiovascular disease increase mortality and hospital readmission risk in patients with dementia?
A history of cardiovascular disease significantly worsens the prognosis of patients with dementia, increasing both mortality and hospital readmission risks.
Elevated risks warrant prognostic awareness in dementia with CVD; leaves open whether management alters outcomes.
OBJECTIVE: To evaluate the impact of cardiovascular disease (CVD) on mortality and readmission risk in patients with dementia. METHODS: Prospective hospital-based cohort of 59 194 patients with dementia admitted to hospital or visiting a day-clinic between 2000 and 2010. Patients were divided in those with and without a history of CVD (ie, previous admission for CVD; coronary heart disease, heart failure, stroke, atrial fibrillation, or other CVD). Absolute mortality risks (ARs), median survival times, and hazard ratios (adjusted for age, sex, and comorbidity) were calculated. RESULTS: Three-year ARs and HRs were higher, and survival times were shorter among patients visiting a day-clinic with a history of CVD than in those without. The differences were less pronounced for inpatients. Readmission risk was further increased in the presence of CVD in both day clinic and inpatients. CONCLUSION: Clinicians need to be more aware of worse prognosis of the population with CVD and dementia.
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Vorst et al. (2018) conducted a cohort in Dementia (n=59,194). History of cardiovascular disease (CVD) vs. No history of CVD was evaluated on Mortality and readmission risk. A history of cardiovascular disease in patients with dementia was associated with higher 3-year mortality and increased readmission risk compared to those without a history of CVD.
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