Key result
Metabolic modulation, including agents that increase glucose oxidation or inhibit free fatty acid oxidation, is reviewed as a therapeutic approach for managing chronic ischemic heart disease.
Population
Patients with chronic ischemic heart disease (stable coronary artery disease)
Design
Review
Authors
Loading...
Metabolic modulation may adjunctively benefit stable CAD patients; leaves open confirmation by large randomized trials.
Metabolic modulation, by shifting energy substrate utilization from fatty acids to glucose, represents a mechanistic therapeutic approach for managing chronic ischemic heart disease and preventing complications like severe left ventricular dysfunction.
Salerno et al. (2010) conducted a review in Chronic Ischemic Heart Disease. Metabolic modulation was evaluated. Metabolic modulation, including agents that increase glucose oxidation or inhibit free fatty acid oxidation, is reviewed as a therapeutic approach for managing chronic ischemic heart disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: