Population
Patients with ischemic heart disease and abnormalities of carbohydrate metabolism, including those with left…
Design
Review
Authors
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May support metabolic modulation in diabetic IHD; leaves open need for confirmatory RCTs before practice change.
Metabolic modulation with FFA oxidation inhibitors like trimetazidine may offer combined benefits for ischemia, ventricular function, and glucose metabolism in diabetic patients with coronary artery disease.
Fragasso et al. (2009) studied this question.
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