Key result
Overlapping PFO occluder deployment successfully achieves complete closure of post-erosion residual shunt.
Case Report (n=1)
Device-related atrial septal erosion is a rare complication of PFO closure that can be successfully managed percutaneously with an overlapping occluder device.
May inform transcatheter options for rare post-PFO septal erosion; hypothesis-generating and requires prospective validation before broader use.
BACKGROUND: Percutaneous patent foramen ovale (PFO) closure is an established method for secondary prevention of paradoxical embolism in patients with cryptogenic stroke. Residual right-to-left shunts after PFO closure are observed in up to 25% of patients. CASE SUMMARY: We present the clinical case of a 56-year-old man with cryptogenic stroke who underwent transcatheter PFO closure. Six months postprocedure, echocardiographic follow-up revealed a progressive residual right-to-left shunt due to marginal septal erosion. A first attempt at transcatheter closure of the residual defect was unsuccessful. Subsequently, a trans-septal puncture with deployment of an overlapping PFO occluder was performed, resulting in complete closure of the residual shunt. DISCUSSION: This case highlights the importance of systematic echocardiographic surveillance and individualized intervention strategies in managing rare device-related complications after PFO closure. TAKE-HOME MESSAGE: Device-related atrial septal erosion is a rare but potentially serious complication, requiring careful assessment and appropriate treatment.
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Kozak et al. (2026) conducted a case report in Cryptogenic stroke and patent foramen ovale with device-related atrial septal erosion (n=1). Trans-septal puncture with deployment of an overlapping PFO occluder was evaluated on Closure of residual shunt. Trans-septal puncture with deployment of an overlapping PFO occluder successfully achieved complete closure of a progressive residual right-to-left shunt caused by marginal septal erosion.
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