Key result
Patients with hypertrophic cardiomyopathy showed significantly lower Tl-201 uptake in the basal septal wall on stress compared to normal controls (78.2% vs 81.3%, p<0.05).
Why the study?
Does dipyridamole Tl-201 SPECT imaging show different perfusion characteristics in patients with hypertrophic cardiomyopathy compared to normal controls?
Case-Control (n=45)
Does dipyridamole Tl-201 SPECT imaging show different perfusion characteristics in patients with hypertrophic cardiomyopathy compared to normal controls?
Dipyridamole Tl-201 SPECT imaging demonstrates regional perfusion abnormalities in patients with hypertrophic cardiomyopathy with asymmetric septal hypertrophy compared to normal controls.
Reversible perfusion defects in HCM remain of uncertain significance; leaves open whether dipyridamole SPECT improves risk stratification.
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Won et al. (1999) conducted a case-control in Hypertrophic cardiomyopathy with asymmetric septal hypertrophy (n=45). Hypertrophic cardiomyopathy vs. Normal controls was evaluated on Tl-201 uptake in basal septal wall on stress (p=<0.05). Patients with hypertrophic cardiomyopathy showed significantly lower Tl-201 uptake in the basal septal wall on stress compared to normal controls (78.2% vs 81.3%, p<0.05).
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