Key result
Multimodality cardiac imaging enables accurate non-invasive diagnosis and risk stratification in cardiac amyloidosis.
Why the study?
Cardiac amyloidosis is a heterogeneous, challenging diagnostic disease with poor prognosis, but advances in multimodality imaging now allow earlier diagnosis, risk stratification, and timely initiation of novel therapies.
Advances in multi-modality cardiac imaging have significantly improved the early diagnosis, risk stratification, and timely initiation of novel therapies for cardiac amyloidosis.
Answers are grounded in this paper and cite their sources.
Supports multi-modality imaging integration in cardiac amyloidosis pathways; leaves open optimal sequencing and outcome impact in prospective studies.
Cardiac amyloidosis is a heterogeneous and challenging diagnostic disease with poor prognosis that is now being altered by introduction of new therapies. Echocardiography remains the first-line imaging tool, and when disease is suspected on echocardiography, cardiac magnetic resonance imaging and nuclear imaging play critical roles in the non-invasive diagnosis and evaluation of cardiac amyloidosis. Advances in multi-modality cardiac imaging allowing earlier diagnosis and initiation of novel therapies have significantly improved the outcomes in these patients. Cardiac imaging also plays important roles in the risk stratification of patients presenting with cardiac amyloidosis. In the current review, we provide a clinical and imaging focused update, and importantly outline the imaging protocols, diagnostic and prognostic utility of multimodality cardiac imaging in the assessment of cardiac amyloidosis.
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Wang et al. (2020) conducted a review in Cardiac amyloidosis. Multi-modality cardiac imaging was evaluated. Multi-modality cardiac imaging, including echocardiography, magnetic resonance imaging, and nuclear imaging, plays a critical role in the non-invasive diagnosis and risk stratification of cardiac amyloidosis.
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