Key result
In a model abdominal aortic aneurysm, wall shear stress and aneurysm width significantly influenced the low density lipoprotein deposition pattern, which was linked to local fluid-flow patterns.
Why the study?
To explore the correlation between wall shear stress, geometric parameters, and the surface concentration variation of low density lipoprotein on the walls of an idealized abdominal aortic aneurysm.
Computational modeling demonstrates that aneurysm width and local fluid-flow patterns, rather than just low wall shear stress, strongly influence LDL deposition in abdominal aortic aneurysms.
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Does not support changing AAA management; leaves open fluid-flow effects on LDL deposition for human validation.
Choudhury et al. (2019) studied Abdominal aortic aneurysm (model). Wall shear stress and geometric parameters was evaluated on LDL surface concentration variation and deposition pattern. In a model abdominal aortic aneurysm, wall shear stress and aneurysm width significantly influenced the low density lipoprotein deposition pattern, which was linked to local fluid-flow patterns.
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