Key result
Type-D personality was associated with higher daily cortisol output compared to non-Type-D patients (4443.3 vs 3252.0 nmol/l; p=0.044) 4 months after an acute coronary syndrome.
Why the study?
Is Type-D personality associated with elevated cortisol levels in survivors of acute coronary syndrome?
Population
70 coronary heart disease patients 4 months after hospitalization for acute coronary syndrome.
Comparison
Type-D personality vs Non Type-D personality
Design
Cross-sectional
Follow-up
4 months post-ACS
Authors
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Type-D personality may mark prolonged HPA dysregulation after ACS; hypothesis-generating and requires prospective confirmation before clinical use.
Observational (n=70)
Is Type-D personality associated with elevated cortisol levels in survivors of acute coronary syndrome?
Absolute Event Rate: 4443.3% vs 3252%
p-value: p=0.044
Type-D personality is associated with prolonged disruption of the HPA axis (higher daily cortisol output) in survivors of acute coronary syndrome.
Molloy et al. (2008) conducted an observational in Acute coronary syndrome (n=70). Type-D personality vs. Non Type-D personality was evaluated on Cortisol output over the day (p=0.044). Type-D personality was associated with higher daily cortisol output compared to non-Type-D patients (4443.3 vs 3252.0 nmol/l; p=0.044) 4 months after an acute coronary syndrome.
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