Key result
Active antihypertensive treatment in patients over 80 years of age reduced stroke events by 53% and stroke mortality by 43%, but was associated with a possible increase in non-stroke deaths.
Why the study?
Does antihypertensive treatment reduce cardiovascular morbidity and mortality in very old patients (>80 years) with hypertension?
Does antihypertensive treatment reduce cardiovascular morbidity and mortality in very old patients (>80 years) with hypertension?
Effect estimate: 53% reduction
No takes yet. Share an insight, caveat, or question.
The benefits of treating uncomplicated hypertension in patients over 80 years remain uncertain, requiring careful clinical judgment until more definitive outcome data are available.
Kjeldsen et al. (2003) conducted an editorial in Hypertension (n=1,283). Thiazide-based regimen or angiotensin-converting enzyme inhibitor vs. No treatment was evaluated on Stroke events (53% reduction). Active antihypertensive treatment in patients over 80 years of age reduced stroke events by 53% and stroke mortality by 43%, but was associated with a possible increase in non-stroke deaths.
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