Key result
Advanced age (r=+0.42), higher heart rate (r=+0.322), and lower LVEF (r=-0.312) were significantly correlated with increased rehospitalization frequency in patients with chronic heart failure.
Why the study?
Chronic heart failure is a major public health problem in Morocco with few studies exploring its specific characteristics, and rehospitalization is strongly correlated with mortality.
Case-Control (n=224)
No
Effect estimate: Pearson correlation +0.42 (age), +0.322 (HR), -0.312 (LVEF)
p-value: p=0.04 (age), p<0.005 (HR), p<0.005 (LVEF)
In a Moroccan cohort of chronic heart failure patients, advanced age, higher heart rate, and lower LVEF were significantly correlated with increased frequency of rehospitalization.
Advanced age, higher HR, and lower LVEF associated with more HF rehospitalizations; supports targeted monitoring but remains hypothesis-generating pending prospective confirmation.
Chronic heart failure (HF) is a major problem of public health in Morocco with few studies exploring HF particularities in this country where the prevalence of HF is estimated to be around 2.2%. Objective: The aim of this study was to evaluate the correlation between frequency of rehospitalization in our population with age, left ventricular ejection fraction (LVEF), heart rate (HR), and QRS duration, Since the number of rehospitalizations is strongly correlated to mortality as shown by many studies. Materials and Methods: Patients with HF were enrolled in this retrospective case control study regardless of their LVEF, patients with recent (<3months) myocardial infarction were excluded. They were all examined and questioned in the heart failure unit of our hospital between the period of October 2022 and December 2022. The correlations were calculated by PEARSON index using R Statistical Software. Results: 224 patients were included. The mean patient age was 59 years (57.2-63;IC 95%) with a male predominance of 60.1 % (56.8-71; IC 95%). 35.5% and 32.2% of patients were treated for hypertension and diabetes respectively. The mean LVEF was 35.2% (33.96-36.91;IC 95%). A positive correlation was found between rehospitalization frequency and age and high heart rate (+ 0.42 p = 0,04;+0.322, p<0.005) respectively . Conversely a negative correlation was found with LVEF (-0.312, p<0.005) while there was a positive correlation with QRS duration but without significance (+0.162 , p=0.03). Conclusion: This study shows strong correlation between rehospitalization and advanced age, higher HR and lower LVEF.
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Couissi et al. (2023) conducted a case-control in Chronic heart failure (n=224). Clinical predictors (age, heart rate, LVEF, QRS duration) was evaluated on Frequency of rehospitalization (Pearson correlation +0.42 (age), +0.322 (HR), -0.312 (LVEF), p=p=0.04 (age), p<0.005 (HR), p<0.005 (LVEF)). Advanced age (r=+0.42), higher heart rate (r=+0.322), and lower LVEF (r=-0.312) were significantly correlated with increased rehospitalization frequency in patients with chronic heart failure.
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