Key result
Hypertension in patients with severe non-rheumatic aortic stenosis was not associated with wider ascending aortic dimensions, whereas bicuspid aortic valve was an independent predictor (p<0.001).
Why the study?
Does hypertension affect ascending aortic dimensions and left ventricular remodeling in patients with severe non-rheumatic aortic stenosis?
Population
225 patients evaluated before surgery for non-rheumatic severe aortic stenosis, mean age 68+/-9 years, 60%…
Comparison
Hypertension vs Normotension
Design
Cross-sectional
Authors
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Hypertension should not alter aortic surveillance in severe non-rheumatic AS; leaves open bicuspid valve-specific dilatation mechanisms.
Cross-Sectional (n=225)
Does hypertension affect ascending aortic dimensions and left ventricular remodeling in patients with severe non-rheumatic aortic stenosis?
In patients with severe non-rheumatic aortic stenosis, coexisting hypertension does not significantly impact ascending aortic dimensions or left ventricular remodeling, whereas bicuspid aortic valve is an independent predictor of aortic dilatation.
Linhartová et al. (2007) conducted a cross-sectional in Severe non-rheumatic aortic stenosis (n=225). Hypertension vs. Normotension was evaluated on Ascending aortic dimensions. Hypertension in patients with severe non-rheumatic aortic stenosis was not associated with wider ascending aortic dimensions, whereas bicuspid aortic valve was an independent predictor (p<0.001).
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