Key result
Patients with ischemic stroke had higher mean carotid intima media thickness compared to age- and sex-matched healthy controls.
Why the study?
Is increased Carotid Intima Media Thickness (CIMT) associated with ischemic stroke?
Case-Control (n=100)
No
Is increased Carotid Intima Media Thickness (CIMT) associated with ischemic stroke?
CIMT measured by carotid Doppler is significantly increased in patients with ischemic stroke, supporting its use as a non-invasive predictor.
Answers are grounded in this paper and cite their sources.
Higher CIMT was associated with ischemic stroke; leaves open its added predictive value beyond traditional risks.
Background: Measurement of Carotid Intima Media Thickness (CIMT) by carotid doppler is a non-invasive, safe and inexpensive investigation. CIMT may predict ischaemic stroke. However, the data about the usefulness of CIMT as a predictor in Indian scenario is relatively less. The primary objective of the present study was to determine utility of CIMT as a predictor of ischemic stroke.Methods: This study was a case control study carried out at a tertiary care institute. The study included fifty cases of ischaemic stroke. Fifty age and sex matched controls were selected who were not relatives of cases.Results: A detailed history of cases and controls was taken. They were subjected to routine investigations; blood sugars and lipid profile were sent. CIMT was measured by doing carotid doppler study on both sided carotid arteries. The results were analysed.Conclusions: From this study, we concluded that there is increase in CIMT in patients of ischemic stroke. Age, gender and side of the vessel had no significant effect on CIMT. It was concluded that CIMT value has a direct correlation with ischemic stroke. Thus, Carotid intima media thickness can be used as a non-invasive predictor of future ischemic stroke incidence.
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Relwani et al. (2017) conducted a case-control in Ischemic stroke (n=100). Ischemic stroke vs. Age and sex matched healthy controls was evaluated on Mean Carotid Intima Media Thickness (Right) (p=<0.01). Patients with ischemic stroke had higher mean carotid intima media thickness compared to age- and sex-matched healthy controls.
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