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June 29, 2022Mediterranean Journal of Hematology and Infectious DiseasesOpen Access

Back to the “Gold Standard”: How Precise Is Hematocrit Detection Today?

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Authors

LLLeonid LivshitsUniversity of ZurichTBTal BiluEmek Medical CenterSPSari PeretzEmek Medical Center

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Implication

Randomized trial compares hematocrit values using automated methods in general and sickle cell disease populations, suggesting better results with ImageJ.

Key Points

  • The research aims to improve hematocrit detection accuracy by utilizing ImageJ software instead of traditional methods.
  • Examined 223 blood samples from the general population and 19 from sickle cell disease patients.
  • Compared hematocrit values from automated HCT, standard micro-HCT, and ImageJ micro-HCT methods.
  • Analyzed discrepancies in MCV and MCHC values among the different detection techniques.
  • ImageJ values were significantly higher than standard micro-HCT and automated HCT for general population samples except newborns (0-2 months).
  • In sickle cell disease patients, ImageJ also showed significantly higher hematocrit compared to micro-HCT and automated HCT.
  • Corresponding discrepancies in MCV and MCHC results were identified with ImageJ over standard methods.

Cite This Study

Livshits et al. (2022) studied this question.

synapsesocial.com/papers/6a5cd6a6fbfab74aebc22cf6https://doi.org/10.4084/mjhid.2022.049
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Also Consider

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  1. 1Blood: tests used to assess the physiological and immunological properties of blood2016 · 26 citations
  2. 2The Influence of Anaemia, Polycythaemia and Splenomegaly on the Relationship between Venous Haematocrit and Red‐Cell Volume1964 · 80 citations
  3. 3Osmotic Properties of Human Red Cells1964 · 203 citations