Key result
A morphologically realistic atrial computer model demonstrated that specific anatomic structures, such as the coronary sinus muscular sheath, play critical roles in stabilizing reentrant circuits.
Why the study?
How do specific anatomic structures affect reentry induction and maintenance in a morphologically realistic atrial model?
Population
Computationally efficient, morphologically realistic computer model of the atria incorporating major…
Design
Preclinical
Authors
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May inform ablation targeting of atrial structures in reentry; leaves open clinical translation pending in vivo validation.
How do specific anatomic structures affect reentry induction and maintenance in a morphologically realistic atrial model?
A morphologically realistic computational model of the atria demonstrates that specific anatomic structures, such as the coronary sinus muscular sheath and venae cavae openings, play critical roles in the induction and maintenance of reentrant circuits.
Vigmond et al. (2001) studied Atrial fibrillation. Selective removal of muscular structures in a computer model was evaluated on Role of specific anatomic structures on reentry induction and maintenance. A morphologically realistic atrial computer model demonstrated that specific anatomic structures, such as the coronary sinus muscular sheath, play critical roles in stabilizing reentrant circuits.
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