February 2, 2009Journal of Cardiovascular Electrophysiology

A Tissue‐Specific Model of Reentry in the Right Atrial Appendage

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Population

Computer model of the right atrial appendage (RAA) based on detailed structural images of a pig RAA

Design

Preclinical

Authors

JZJichao ZhaoElectrophysiology MTMark L. TrewUniversity of Auckland ILIan J. LeGriceUniversity of Auckland

Discussion

Member takes

Implication

Informs CT reentry mechanisms in animal models; hypothesis-generating for human AF ablation targets.

Structured PICO

Population

Computer model of the right atrial appendage (RAA) based on detailed structural images of a pig RAA

Intervention

Train of reducing cycle length stimuli applied to a crista terminalis (CT) / pectinate muscle (PM) junction in the computer model

Outcome

Mechanisms of conduction block and reentry (functional block parallel with and perpendicular to the axis of the CT)surrogate

A tissue-specific computer model of the right atrial appendage demonstrates that high anisotropy and reduced safety factor, rather than regional refractory period differences, drive conduction block and reentry.

Cite This Study

Zhao et al. (2009) studied this question.

synapsesocial.com/papers/6a91103b33d44bf09c744c81 https://doi.org/10.1111/j.1540-8167.2008.01420.x

View Full Paper

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Bookmark

A Tissue‐Specific Model of Reentry in the Right Atrial Appendage

Discussion

Member takes

Implication

Structured PICO

Cite This Study

A Tissue‐Specific Model of Reentry in the Right Atrial Appendage

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider