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This paper examines how atmospheric pressure plasma interacts with biological liquids to influence wound and cancer treatments.

Air plasma treatment of liquid covered tissue: long timescale chemistry

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Computational investigation reveals plasma-liquid interactions affecting wound and tumor treatments, indicating optimization pathways.

This paper examines how atmospheric pressure plasma interacts with biological liquids to influence wound and cancer treatments.
Simulated 5000 voltage pulses from a dielectric barrier discharge over liquid covered tissue.
Investigated the effects of various parameters including pulse repetition frequency and organic molecules in the liquid.
Implemented a global model to address the dynamic range of chemical reactions and timescales.
Gas phase dynamics change significantly by the 5000th discharge pulse compared to the first due to long-lived species such as ozone and nitrogen oxides.
Variation in applied voltage and gas flow affects the generation of reactive species in both gas and liquid phases.
Found that the presence of organic molecules alters the reactive chemistry involved in plasma treatment.

Lietz et al. (2016) studied this question.

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