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November 24, 2008Archives of Internal Medicine

A Randomized Trial of the Effect of Community Pharmacist and Nurse Care on Improving Blood Pressure Management in Patients With Diabetes Mellitus

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Key result

A community pharmacist and nurse team-based intervention resulted in a 5.6 mm Hg greater reduction in systolic blood pressure at 6 months compared with usual care (P=0.008).

Why the study?

Does a community-based pharmacist and nurse team intervention reduce systolic blood pressure in patients with diabetes mellitus and elevated blood pressure?

Population

227 patients with diabetes mellitus and blood pressure > 130/80 mm Hg on 2 consecutive visits 2 weeks apart…

Comparison

Community-based multidisciplinary care from a… vs BP wallet card, a pamphlet on diabetes, general…

Design

RCT, Randomized to intervention and control arms

Follow-up

6 months

Authors

DMDonna McLeanAlberta Health Services

Discussion

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Implication

Pharmacist-nurse teams reduce systolic BP 5.6 mm Hg more than usual care in diabetes; extends RCT evidence for community team-based hypertension management.

Key Points

  • To determine the efficacy of a community-based multidisciplinary intervention on blood pressure control in patients with diabetes mellitus.
  • Conducted randomized controlled trial in 14 community pharmacies in Edmonton, Alberta.
  • Included participants with systolic blood pressure higher than 130/80 mm Hg on 2 consecutive visits.
  • Intervention involved pharmacist and nurse team providing education and follow-up over 6 months.
  • Intervention group had a greater mean reduction in systolic blood pressure of 5.6 mm Hg compared with controls (P = .008).
  • In patients with baseline systolic BP > 160 mm Hg, the intervention resulted in a 24.1 mm Hg reduction compared to controls (P < .001).

Study Design

Type

RCT (n=227)

Randomization

randomized

Multicenter

Yes

Structured PICO

Does a community-based pharmacist and nurse team intervention reduce systolic blood pressure in patients with diabetes mellitus and elevated blood pressure?

P
Population
227 patients with diabetes and blood pressure >130/80 mm Hg, followed for 6 months.
I
Intervention
Community-based multidisciplinary care from a pharmacist and nurse team, including a wallet card with recorded BP measures, cardiovascular risk reduction education and counseling, a hypertension education pamphlet, referral to the patient's primary care physician, a 1-page evidence summary sent to the physician, and 4 follow-up visits throughout 6 months.
C
Comparator
BP wallet card, a pamphlet on diabetes, general diabetes advice, and usual care by their physician.
O
Outcome
Difference in change in systolic BP between the 2 groups at 6 months.surrogate

Main Result

Mean Difference: -5.6

p-value: p=0.008

A community-based pharmacist and nurse team intervention significantly improves systolic blood pressure control in patients with diabetes compared to usual care.

Cite This Study

Donna McLean (2008) conducted an RCT in Diabetes mellitus and hypertension (n=227). Community pharmacist and nurse care vs. Usual care was evaluated on Difference in change in systolic BP between the 2 groups at 6 months (MD -5.6 mm Hg, p=0.008). A community pharmacist and nurse team-based intervention resulted in a 5.6 mm Hg greater reduction in systolic blood pressure at 6 months compared with usual care (P=0.008).

synapsesocial.com/papers/6a5d4d5bfb7682ce97c23d2bhttps://doi.org/10.1001/archinte.168.21.2355

Topics

Hypertension managementWomen and heart disease
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pharmacist Intervention Program for Control of Hypertension2003 · 157 citations
  2. 2Diabetes, fibrinogen, and risk of cardiovascular disease: The Framingham experience1990 · 372 citations
  3. 3Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials2003 · 1,247 citations
  4. 4Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 381998 · 4,816 citations