Key result
Combined aortic valve, root, and ascending aorta replacement using a composite stentless valve with graft extension resulted in zero operative mortality in a series of 8 patients.
Why the study?
Does combined aortic valve, root, and ascending aorta replacement with a composite stentless valve and graft extension result in safe perioperative outcomes in patients with severe aortic root and ascending aortic pathology?
Observational (n=8)
Does combined aortic valve, root, and ascending aorta replacement with a composite stentless valve and graft extension result in safe perioperative outcomes in patients with severe aortic root and ascending aortic pathology?
A composite stentless porcine valve with graft extension is a feasible and safe alternative to mechanical conduits for combined aortic root and ascending aorta replacement, avoiding the need for long-term anticoagulation.
OBJECTIVE: The composite mechanical valve conduit has been most commonly used for patients who require combined aortic valve, root, and ascending aorta replacement, but is limited, especially in the elderly, because of the need for long-term anticoagulation. We report the first consecutive series of patients in whom a composite stentless valve with graft extension, which does not require long-term anticoagulation, was performed. METHODS: Between April 1998 and July 2000, eight patients with severe aortic root and ascending aortic pathology underwent a combined aortic valve, root, and ascending aorta replacement with a Freestyle stentless porcine valve with a Hemashield graft extension. Mean age was 74 (range 56--82), three were males. Concomitant procedures included coronary artery bypass graft (CABG) alone (n=2), mitral valve replacement with atrial septal defect repair (n=1) and CABG with septal myomectomy (n=1). RESULTS: Operative mortality was zero. Median aortic cross-clamp and cardiopulmonary bypass times were 150 and 203 min, respectively. Two patients returned to the operating room for bleeding. Median blood transfusions and hospital length of stay were 4 units and 11 days, respectively. CONCLUSIONS: The composite stentless valve with graft extension is a reasonable alternative to a mechanical valve conduit for patients who require a combined aortic valve, root, and ascending aorta replacement, in whom anticoagulation is not desirable or contraindicated.
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Byrne et al. (2001) conducted an observational in Severe aortic root and ascending aortic pathology (n=8). Composite stentless valve with graft extension (Freestyle stentless porcine valve with Hemashield graft) was evaluated on Operative mortality. Combined aortic valve, root, and ascending aorta replacement using a composite stentless valve with graft extension resulted in zero operative mortality in a series of 8 patients.
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