Key result
Histopathology of a retrieved white, fibrin- and platelet-rich thrombus aids diagnosis of cancer-associated stroke.
Why the study?
Diagnosing cancer-associated stroke is challenging because active cancer does not necessarily indicate a causal link with stroke.
Case Report (n=1)
No
Histopathological analysis of retrieved thrombi from mechanical thrombectomy can aid in the diagnostic evaluation of cancer-associated stroke.
Answers are grounded in this paper and cite their sources.
Thrombus histology from thrombectomy may aid cancer-associated stroke diagnosis; leaves open whether this extends beyond case-level observation.
The diagnosis of cancer-associated stroke is challenging because the presence of active cancer does not necessarily indicate a causal association with stroke. Recent advances in mechanical thrombectomy have enabled the histopathological analysis of retrieved thrombi. In contrast to thrombi associated with conventional stroke etiologies, those associated with cancer have been reported to have a white gross appearance and to be rich in fibrin and platelets. We report a case in which the histological features of a retrieved thrombus provided important clues for diagnosing cancer-associated stroke. A histopathological analysis of a retrieved thrombi may contribute to the diagnostic evaluation of cancer-associated stroke.
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Kudo et al. (2026) conducted a case report in Cancer-associated stroke (n=1). Histopathological examination of retrieved thrombus was evaluated. Histopathological examination of a retrieved thrombus revealing a white, fibrin- and platelet-rich composition provided crucial clues for diagnosing cancer-associated stroke in an 87-year-old man.
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