Key result
Unaccustomed eccentric muscle exercise causes structural damage to muscle fibers, hypothesized to be driven by fiber strain magnitude and oxidative capacity rather than absolute stress.
Population
Animal and human muscle fibers
Design
Review
Authors
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Strain magnitude may guide eccentric training limits; leaves open validation for injury prevention.
This review proposes that exercise-induced muscle injury is driven by fiber strain magnitude and occurs early during eccentric exercise, predominantly affecting fast-twitch glycolytic fibers.
Fridén et al. (1992) conducted a review in Exercise-induced muscle injury. Unaccustomed eccentric muscle exercise was evaluated on Muscle fiber contractile and cytoskeletal damage. Unaccustomed eccentric muscle exercise causes structural damage to muscle fibers, hypothesized to be driven by fiber strain magnitude and oxidative capacity rather than absolute stress.
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