Key result
Mitral valve repair linked to ~30% higher 5-year survival versus replacement in native endocarditis.
Why the study?
Although valve repair should be preferred in surgical patients with mitral valve endocarditis, the decision between valve reconstruction and valve replacement remains nuanced.
Does mitral valve repair improve survival compared to mitral valve replacement in patients undergoing surgery for native mitral valve endocarditis?
Population
281 consecutive patients undergoing surgery for native mitral valve endocarditis
Comparison
Mitral valve repair vs mitral valve replacement
Design
Single-center retrospective cohort study with propensity score matching
Follow-up
Mean 5.2 ± 5.1 years
Authors
Loading...
Repair may be preferable when feasible; supports preservation strategies but leaves causal benefit open pending randomized data.
Cohort (n=281)
No
Does mitral valve repair improve survival compared to mitral valve replacement in patients undergoing surgery for native mitral valve endocarditis?
Absolute Event Rate: 92.6% vs 62.4%
p-value: p=0.034
Mitral valve repair is associated with significantly better long-term survival compared to replacement in patients with native mitral valve endocarditis, supporting the use of valve preservation techniques when feasible.
Dzilic et al. (2025) conducted a cohort in Native mitral valve endocarditis (n=281). Mitral valve repair vs. Mitral valve replacement was evaluated on 5-year survival (propensity score matched) (p=0.034). Mitral valve repair for native mitral valve endocarditis was associated with significantly better 5-year survival compared to valve replacement (92.6% vs. 62.4%, p=0.034) after propensity matching.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: