Key result
Mitral valve repair for endocarditis was associated with lower in-hospital mortality compared to replacement (4% vs 7%; OR 0.65, 95% CI 0.43-0.97, p=0.034).
Why the study?
The optimal surgical approach for mitral valve endocarditis remains controversial, with conflicting evidence regarding whether mitral valve repair yields better outcomes than replacement.
Does mitral valve repair reduce in-hospital mortality compared to mitral valve replacement in patients with mitral valve endocarditis?
Cohort (n=4,657)
Yes
Does mitral valve repair reduce in-hospital mortality compared to mitral valve replacement in patients with mitral valve endocarditis?
Odds Ratio: 0.65 (95% CI 0.43–0.97)
Absolute Event Rate: 4% vs 7%
p-value: p=0.034
Mitral valve repair for endocarditis is associated with lower in-hospital mortality and fewer early postoperative complications compared to valve replacement.
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Retrospective MVr vs MVR data in endocarditis are hypothesis-generating; prospective trials needed before practice change.
Al-Zubaidi et al. (2025) conducted a cohort in Mitral valve endocarditis (n=4,657). Mitral valve repair vs. Mitral valve replacement was evaluated on In-hospital mortality (OR 0.65, 95% CI 0.43-0.97, p=0.034). Mitral valve repair for endocarditis was associated with lower in-hospital mortality compared to replacement (4% vs 7%; OR 0.65, 95% CI 0.43-0.97, p=0.034).
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