Key result
Proton magnetic resonance spectroscopy noninvasively confirmed a massive accumulation of myocardial triglyceride (4.92%) in a patient with triglyceride deposit cardiomyovasculopathy.
Why the study?
Can proton magnetic resonance spectroscopy noninvasively confirm massive accumulation of triglyceride in the myocardium of a patient with triglyceride deposit cardiomyovasculopathy?
Case Report (n=1)
No
Can proton magnetic resonance spectroscopy noninvasively confirm massive accumulation of triglyceride in the myocardium of a patient with triglyceride deposit cardiomyovasculopathy?
This is the first report to noninvasively confirm massive myocardial triglyceride accumulation in a patient with triglyceride deposit cardiomyovasculopathy using 1H-MRS.
1H-MRS may enable noninvasive detection of myocardial TG accumulation in triglyceride deposit cardiomyovasculopathy; hypothesis-generating and requires prospective validation.
The patient was a 73-year-old man with a history of hypertension, diabetes mellitus, dyslipidemia, rheumatoid arthritis, repeated percutaneous coronary intervention and percutaneous peripheral intervention procedures. He was frequently admitted to our hospital for congestive heart failure with orthopnea. The myocardial washout rate of iodine-123-β-methyl iodophenyl-pentadecanoic acid was defective on scintigraphy. He was diagnosed with triglyceride deposit cardiomyovasculopathy (TGCV). Proton magnetic resonance spectroscopy (1H-MRS) indicated the level of myocardial triglyceride (TG) content to be extremely high (4.92%). This is the first report to confirm a massive accumulation of TG in the myocardium of a patient with TGCV using 1H-MRS noninvasively.
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Sai et al. (2020) conducted a case report in Triglyceride deposit cardiomyovasculopathy (n=1). Proton magnetic resonance spectroscopy (1H-MRS) was evaluated on Myocardial triglyceride content. Proton magnetic resonance spectroscopy noninvasively confirmed a massive accumulation of myocardial triglyceride (4.92%) in a patient with triglyceride deposit cardiomyovasculopathy.
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