Key result
Elevated high-sensitivity troponin T measured immediately after valve surgery was independently associated with a higher risk of postoperative sudden cardiac arrest (OR 1.304).
Why the study?
The usefulness of high-sensitivity troponin T as a predictor of sudden cardiac arrest in patients undergoing valve surgery was unknown.
Does postoperative high-sensitivity troponin T predict sudden cardiac arrest in patients undergoing elective valve surgery?
Cohort (n=815)
No
Does postoperative high-sensitivity troponin T predict sudden cardiac arrest in patients undergoing elective valve surgery?
Odds Ratio: 1.304 (95% CI 1.201–1.409)
p-value: p=0.004
Elevated high-sensitivity troponin T measured immediately after elective valve surgery is an independent predictor of postoperative sudden cardiac arrest.
Elevated postoperative hs-TnT may identify SCA risk after valve surgery; hypothesis-generating and should not yet change practice.
BACKGROUND: The usefulness of high-sensitivity troponin T (hs-TnT) as a predictor of sudden cardiac arrest (SCA) in patients undergoing valve surgery is currently unknown. METHODS: A prospective study was conducted on a group of 815 consecutive patients with significant valvular heart disease that underwent elective valve surgery. The primary end-point was postoperative SCA. RESULTS: The postoperative SCA occurred in 26 patients. At multivariate analysis of hs-TnT measured immediately after surgery (hs-TnT I) and age remained independent predictors of the primary end-point. CONCLUSIONS: Elevated postoperative hs-TnT was associated with a higher risk of postoperative SCA.
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Duchnowski et al. (2019) conducted a cohort in Hemodynamically significant valve defects (n=815). High-sensitivity troponin T measured immediately after surgery (hs-TnT I) vs. Lower levels of hs-TnT I was evaluated on Postoperative sudden cardiac arrest (SCA) (OR 1.304, 95% CI 1.201-1.409, p=0.004). Elevated high-sensitivity troponin T measured immediately after valve surgery was independently associated with a higher risk of postoperative sudden cardiac arrest (OR 1.304).
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