Key result
Moderate-to-low LMWH adherence is linked to lower treatment satisfaction and more injection site adverse events.
Why the study?
Data on patient adherence and satisfaction with prophylactic low molecular weight heparin after orthopaedic trauma surgery are lacking.
Cohort (n=100)
Mean Difference: 2 (95% CI 0.9–3.2)
p-value: p=<0.001
Nearly half of orthopaedic trauma patients report moderate or low adherence to self-administered prophylactic LMWH, which is associated with more injection site adverse events and lower satisfaction.
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May inform counseling on post-trauma LMWH self-injection; leaves open optimal adherence strategies in routine practice.
Horzum et al. (2026) conducted a cohort in Orthopaedic trauma surgery (n=100). Moderate or low adherence to prophylactic LMWH vs. High adherence to prophylactic LMWH was evaluated on Satisfaction with treatment (ACTS Benefits scale score) (MD 2.0, 95% CI 0.9-3.2, p=<0.001). Moderate or low adherence to prophylactic LMWH after orthopaedic trauma surgery was associated with lower treatment satisfaction (MD 2.0; 95% CI 0.9-3.2; P<0.001) and more injection site adverse events.
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