Key result
Platelet adhesion measured by the Impact-R device decreased significantly during 7-day storage in apheresis (11.6% to 7.4%) and buffy coat (8.5% to 5.9%) concentrates.
Population
40 platelet concentrates reconstituted with red cells
Design
Preclinical
Follow-up
7 days
Authors
Loading...
Impact-R may track platelet changes in storage; leaves open clinical utility without validation trials.
The Impact-R device can detect significant declines in platelet adhesion and aggregation during the storage of platelet concentrates, suggesting utility for monitoring platelet storage lesions.
Albanyan et al. (2009) studied Platelet storage lesion (n=40). Impact-R test was evaluated on Surface coverage (measure of adhesion) and average size (measure of aggregation). Platelet adhesion measured by the Impact-R device decreased significantly during 7-day storage in apheresis (11.6% to 7.4%) and buffy coat (8.5% to 5.9%) concentrates.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: