Synthetic methodology for alkyl substituted hydrazines

Substituted hydrazines have found many technical and commercial applications and this is reflected in the immense number of such compounds synthesized to date. In this review an attempt has been made to supplement the existing comprehensive literature by presenting only a selection of synthetic methods, judged to be of particular principal or practical interest, together with some additional, recent approaches. The important steps in the development from simple substituted hydrazines to rational synthesis of multisubstituted derivatives are recapitulated.