Key result
Oral anticoagulation was associated with a significantly higher rate of capillary bleedings compared to controls (74.2% vs 7.7%, p<0.001), though this did not predict future clinical hemorrhage.
Why the study?
Does oral anticoagulation increase capillary bleeding in patients compared to controls?
Observational (n=83)
Does oral anticoagulation increase capillary bleeding in patients compared to controls?
Absolute Event Rate: 74.2% vs 7.7%
p-value: p=<0.001
While oral anticoagulation frequently causes capillary bleedings independent of INR, these microvascular events do not predict future clinically significant hemorrhage.
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Frequent capillary bleedings on oral anticoagulation appear unrelated to major hemorrhage risk; leaves open the value of microvascular monitoring in future studies.
Leithäuser et al. (2009) conducted an observational in Cardiac, arterial or venous diseases (n=83). Oral anticoagulation vs. No oral anticoagulation was evaluated on Presence of capillary bleedings (p=<0.001). Oral anticoagulation was associated with a significantly higher rate of capillary bleedings compared to controls (74.2% vs 7.7%, p<0.001), though this did not predict future clinical hemorrhage.
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