Key result
CTA shows low concordance with TEE for detecting LAA thrombus, agreeing in ~26% of cases.
Why the study?
Although TEE is the gold standard for diagnosing LAA thrombus, CTA is readily used before PVI and LAA closure, prompting evaluation of the comparability between modalities.
Does computerized tomography angiography (CTA) accurately diagnose left atrial appendage thrombus compared to transesophageal echocardiography (TEE) in patients with atrial fibrillation?
Observational (n=63)
Does computerized tomography angiography (CTA) accurately diagnose left atrial appendage thrombus compared to transesophageal echocardiography (TEE) in patients with atrial fibrillation?
p-value: p=0.01902
CTA and TEE show low concordance for diagnosing LAA thrombus in patients with atrial fibrillation, suggesting they should be used as complementary rather than interchangeable tests.
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Discordant LAA thrombus detection between CTA and TEE warrants clinical caution; leaves open need for prospective validation studies.
Bloch-Isenberg et al. (2023) conducted an observational in Atrial fibrillation (n=63). Computerized tomography angiography (CTA) vs. Transesophageal echocardiography (TEE) was evaluated on Concordance of LAA thrombus diagnosis (p=0.01902). Computerized tomography angiography demonstrated low concordance with transesophageal echocardiography for detecting left atrial appendage thrombus, with only 26.1% of cases identified by both (P=0.019).
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