Key result
Radiotherapy and combination chemotherapy in adult Ewing sarcoma yielded a 35% tumor-free survival at 27 months for primary presentations, whereas all patients with primary pelvic tumors died.
Why the study?
What are the outcomes of radiotherapy and combination chemotherapy in adult patients with Ewing sarcoma?
Population
50 adult patients with Ewing sarcoma (34 with primary presentation, 16 with locally recurrent or metastatic)
Design
Case_series
Follow-up
27 to 36 months
Authors
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Pelvic presentations carry dismal prognosis; hypothesis-generating for site-specific intensification in adult Ewing sarcoma.
Observational (n=50)
What are the outcomes of radiotherapy and combination chemotherapy in adult patients with Ewing sarcoma?
In adult patients with Ewing sarcoma, combination chemotherapy and radiotherapy yielded a 35% tumor-free survival at 27 months for primary presentations, though pelvic presentations had uniformly fatal outcomes.
Sinkovics et al. (2009) conducted an observational in Ewing sarcoma (n=50). Radiotherapy and combination chemotherapy was evaluated on Tumor-free survival at 27 months (primary presentation group). Radiotherapy and combination chemotherapy in adult Ewing sarcoma yielded a 35% tumor-free survival at 27 months for primary presentations, whereas all patients with primary pelvic tumors died.
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