Key result
Surgical treatment of primary osseous Ewing's sarcoma improves local control and possibly survival, with five-year survival rates for localized disease now ranging from 54% to 74%.
Advances in multimodal treatment including surgery, radiotherapy, and chemotherapy have improved five-year survival rates for localized osseous Ewing's sarcoma to 54-74%.
Local control strategies warrant priority in Ewing sarcoma; leaves open optimal multimodal regimens in contemporary cohorts.
Advances in the treatment of Ewing's sarcoma have been dramatic. Present treatment protocols control local disease by radiotherapy, surgery, or both; systemic spread is limited by aggressive multiagent chemotherapy. In patients with localized osseous Ewing's sarcoma, five-year survival rates now range from 54% to an estimated 74%. With late relapse not uncommon, control of the primary lesion is critical to long-term survival. Several studies now show improved local control and possibly improved survival of patients with surgical treatment of primary osseous Ewing's sarcoma.
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O'CONNOR et al. (1991) conducted a review in Ewing's sarcoma. Surgical treatment, radiotherapy, and multiagent chemotherapy was evaluated on Five-year survival rate. Surgical treatment of primary osseous Ewing's sarcoma improves local control and possibly survival, with five-year survival rates for localized disease now ranging from 54% to 74%.
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