Key result
Complete surgical resection is preferred to irradiation for local control in Ewing's sarcoma of the mandible when it can be performed with minimal loss of function and disfigurement.
Why the study?
Does complete surgical resection improve local control compared to irradiation in patients with Ewing's sarcoma of the mandible?
Does complete surgical resection improve local control compared to irradiation in patients with Ewing's sarcoma of the mandible?
Complete surgical resection is preferred to irradiation for local control of Ewing's sarcoma of the mandible when surgery can be performed with minimal loss of function.
Supports preferring surgery for mandibular Ewing sarcoma when feasible; leaves open prospective validation in modern cohorts.
Cure rates of Ewing's sarcoma have improved from 10% to 75% with the use of a combination of local therapy and aggressive multi-drug chemotherapy, to decrease both the incidence of local disease recurrence and the development of pulmonary and skeletal metastases. In Ewing's sarcoma of the mandible, complete surgical resection is preferred to irradiation for local control in those instances when surgery can be performed with minimal loss of function and disfigurement.
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Langman et al. (1989) conducted a review in Ewing's sarcoma of the mandible. Complete surgical resection vs. Irradiation was evaluated. Complete surgical resection is preferred to irradiation for local control in Ewing's sarcoma of the mandible when it can be performed with minimal loss of function and disfigurement.
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