Key result
Radiation and sequential adjuvant chemotherapy treat rare mandibular Ewing's sarcoma presenting in the second decade.
Why the study?
Ewing's sarcoma of the mandible is rare with fewer than 50 reported cases in 30 years and none in otolaryngologic literature.
Ewing's sarcoma of the mandible is a rare condition typically presenting in the second decade of life, diagnosed via biopsy, and treated with radiation and chemotherapy.
Supports biopsy-directed diagnosis and multimodal therapy for rare mandibular Ewing sarcoma; leaves open optimal protocols given Level 5 evidence.
Ewing's sarcoma of the mandible occurs rarely; there have been less than 50 reported cases in the past 30 years and none of these have been in the otolaryngologic literature. They usually present in the second decade of life with pain and swelling of the soft tissue overlying the mandible. The diagnosis can only be made by an adequate mandibular biopsy, although x-rays and clinical presentation are helpful. Current treatment consists of radiation therapy and sequential adjuvant chemotherapy.
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Bernstein et al. (1979) conducted a review in Ewing's sarcoma of the mandible. Radiation therapy and sequential adjuvant chemotherapy was evaluated. Ewing's sarcoma of the mandible is a rare condition typically presenting in the second decade of life, diagnosed via biopsy, and treated with radiation and sequential adjuvant chemotherapy.
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