What question did this study set out to answer?

This study aims to determine how the geriatric nutritional risk index (GNRI) affects long-term outcomes in esophageal squamous cell carcinoma (ESCC) patients post-surgery.

September 20, 2018Nutrition and Cancer

The Prognostic Significance of the Geriatric Nutritional Risk Index in Patients with Esophageal Squamous Cell Carcinoma

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Authors

KMKazuhiro MigitaNara Medical University SMSohei MatsumotoNara Medical University KWKohei WakatsukiEducation Development Center

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Implication

Randomized trial investigates the role of GNRI on overall survival in esophageal cancer patients, suggesting it as a key prognostic tool.

Key Points

This study aims to determine how the geriatric nutritional risk index (GNRI) affects long-term outcomes in esophageal squamous cell carcinoma (ESCC) patients post-surgery.
137 esophageal squamous cell carcinoma patients underwent curative esophagectomy.
GNRI was calculated using serum albumin and body weight, with a cutoff at 98.
A multivariate analysis evaluated the relationship between GNRI and overall survival.
The GNRI was significantly correlated with tumor depth (p = 0.001) and levels of CEA (p = 0.009) and CRP (p = 0.028).
Patients with a low GNRI (<98) had a higher risk of death from esophageal cancer (p = 0.004).
The GNRI was identified as an independent predictor for overall survival (p < 0.001).

Cite This Study

Migita et al. (2018) studied this question.

synapsesocial.com/papers/6a5e32f1ffe7d48a36d892a9 https://doi.org/10.1080/01635581.2018.1512640

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The Prognostic Significance of the Geriatric Nutritional Risk Index in Patients with Esophageal Squamous Cell Carcinoma

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Implication

Key Points

Cite This Study

The Prognostic Significance of the Geriatric Nutritional Risk Index in Patients with Esophageal Squamous Cell Carcinoma

Discussion

Member takes

Implication

Key Points

Cite This Study

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