Advances in Prosthetic Heart Valves: Fluid Mechanics of Aortic Valve Designs

Q: What is the clinical evidence from this study?

Population: Prosthetic heart valves. Intervention: Heart valve designs after 1975 vs. Heart valve designs prior to 1975. Primary outcome: Hemodynamic characteristics (performance indices, regurgitant volumes, flow fields).

Ajit P. Yoganathan; Yi‐Ren Woo; Hsing‐Wen Sung; Michael Jones

doi:10.1177/088532828700200405

October 1, 1987Journal of Biomaterials Applications

Advances in Prosthetic Heart Valves: Fluid Mechanics of Aortic Valve Designs

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Key Points

To investigate the fluid mechanics and hemodynamic performance of various mechanical and tissue heart valve designs.
In vitro study of various mechanical and tissue heart valves under pulsatile flow conditions.
Evaluation of pressure drop, regurgitant volumes, and flow characteristics,
Valves designed prior to 1975 had performance indices of 0.30 to 0.45; those after 1975 ranged from 0.40 to 0.70.
Mechanical designs had higher regurgitant volumes (5.0 to 11.0 cm3/beat) compared to tissue bioprostheses (1.0 to 5.0 cm3/beat).
Current designs create significant areas of stasis and turbulent shear stresses that can damage blood components.

Structured PICO

P

Population

In vitro models of mechanical and tissue heart valves in the aortic position under pulsatile flow conditions

E

Exposure

Prosthetic heart valve designs introduced after 1975 (Medtronic-Hall tilting disc, St. Jude Medical bileaflet, Hancock porcine model 250, Hancock II porcine model 410, Carpentier-Edwards porcine model 2650, Carpentier-Edwards pericardial model 2900)

C

Comparator

Prosthetic heart valve designs introduced prior to 1975 (Starr-Edwards ball and cage model 1260, Björk-Shiley tilting disc, Carpentier-Edwards porcine model 2625, Ionescu-Shiley standard pericardial)

O

Outcome

In vitro hemodynamic characteristics including pressure drop, performance indices, regurgitant volumes, and flow fieldssurrogate

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Implication

Newer prosthetic heart valve designs (post-1975) demonstrate improved hemodynamic performance indices and centralized flow compared to older designs, though all current models still exhibit non-ideal flow characteristics that may damage blood elements.

Abstract

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Cite This Study

Yoganathan et al. (1987) studied Prosthetic heart valves. Heart valve designs after 1975 vs. Heart valve designs prior to 1975 was evaluated on Hemodynamic characteristics (performance indices, regurgitant volumes, flow fields).

synapsesocial.com/papers/6a5e382844d40cfb0237c7a9 https://doi.org/10.1177/088532828700200405

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Advances in Prosthetic Heart Valves: Fluid Mechanics of Aortic Valve Designs

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Advances in Prosthetic Heart Valves: Fluid Mechanics of Aortic Valve Designs

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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