Key result
Age-adjusted percentage of reticulated platelets was significantly higher in patients in the early (P=0.047) and late phases (P=0.01) after ischaemic stroke or TIA compared to controls.
Why the study?
Is the percentage of reticulated platelets increased in the early and late phases after ischaemic stroke or TIA compared to controls?
Population
Patients in the early and late phases after ischaemic stroke or transient ischaemic attack, and controls…
Comparison
Measurement of percentage of reticulated… vs Controls without cerebrovascular disease (n=27).
Design
Cohort
Authors
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May support reticulated platelets as a biomarker in cerebrovascular disease; leaves open prognostic or therapeutic implications pending prospective studies.
Observational (n=176)
Is the percentage of reticulated platelets increased in the early and late phases after ischaemic stroke or TIA compared to controls?
p-value: p=0.047 (early), 0.01 (late)
The percentage of reticulated platelets is modestly elevated after ischaemic stroke or TIA when adjusted for age, and correlates with mean platelet volume, but does not strongly support excessive platelet production.
McCabe et al. (2004) conducted an observational in Ischaemic stroke or transient ischaemic attack (n=176). Ischaemic stroke or TIA vs. Controls without cerebrovascular disease was evaluated on Percentage of reticulated platelets (% RP) (p=0.047 (early), 0.01 (late)). Age-adjusted percentage of reticulated platelets was significantly higher in patients in the early (P=0.047) and late phases (P=0.01) after ischaemic stroke or TIA compared to controls.
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