Key result
Heartland virus infection can cause rapidly fatal, widely disseminated disease with multisystem organ failure in patients without substantial comorbidities, involving previously undetected tissues.
Heartland virus can cause rapidly fatal, widely disseminated infection with multisystem organ failure even in patients without substantial comorbidities, with viral antigen detectable in multiple novel organ tissues.
We describe an investigation into a Heartland virus (HRTV)-associated death in Tennessee with novel clinical and pathologic findings. HRTV can cause rapidly fatal, widely disseminated infection with multisystem organ failure in patients without substantial comorbidities. We identified viral antigen in multiple organ tissues where it was not detected previously.
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Fill et al. (2016) studied this question. Heartland virus infection can cause rapidly fatal, widely disseminated disease with multisystem organ failure in patients without substantial comorbidities, involving previously undetected tissues.
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