Key result
Recent evidence from intact and denervated models supports a hyperadditive or synergistic interaction between peripheral and central chemoreceptors in respiratory motor control.
This debate article argues that peripheral and central chemoreceptors interact synergistically (hyperadditively) to modulate respiratory motor control, which may have implications for understanding breathing disorders.
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Non-additive chemoreceptor interactions question isolated contribution estimates; leaves open integrated models for ventilatory control research.
Teppema et al. (2013) conducted an editorial in Respiratory motor control. Peripheral and central chemoreceptor interaction was evaluated. Recent evidence from intact and denervated models supports a hyperadditive or synergistic interaction between peripheral and central chemoreceptors in respiratory motor control.
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