Key result
Each standard deviation decrease in retinal arteriolar diameter was associated with a 38% increased risk of incident hypertension (OR 1.38).
Why the study?
Does retinal vessel narrowing predict the development of incident hypertension in adults ≥55 years of age?
Population
1900 participants from the prospective population-based Rotterdam Study, including 739 persons with normal…
Design
Cohort
Follow-up
mean 6.6 years
Authors
Loading...
Retinal arteriolar measures may refine hypertension risk prediction in older adults; leaves open added clinical value beyond standard factors.
Cohort (n=1,900)
No
Does retinal vessel narrowing predict the development of incident hypertension in adults ≥55 years of age?
Odds Ratio: 1.38 (95% CI 1.23–1.55)
Both retinal arteriolar and venular narrowing independently predict the development of systemic hypertension in older adults.
Ikram et al. (2005) conducted a cohort in Normal blood pressure or prehypertension (n=1,900). Retinal arteriolar narrowing vs. Wider retinal arteriolar diameters was evaluated on Incident hypertension (systolic BP ≥140 mm Hg, diastolic BP ≥90 mm Hg, or use of antihypertensive medication) (OR 1.38, 95% CI 1.23 to 1.55). Each standard deviation decrease in retinal arteriolar diameter was associated with a 38% increased risk of incident hypertension (OR 1.38).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: