Why the study?
Superior TAVR outcomes occur with transfemoral access, but many patients remain ineligible due to peripheral arterial disease precluding large-diameter delivery systems.
Observational
Registry evaluation of lithotripsy for TAVR access is hypothesis-generating; randomized trials needed before clinical adoption.
Randomized controlled trials of transcatheter aortic valve replacement (TAVR) included both transfemoral and alternative access approaches for valve delivery (1), but the best outcome, superiority to surgical aortic valve replacement, was only achieved in transfemoral patients (2,3). Unfortunately, a significant number of patients remain ineligible for routine transfemoral access due to peripheral arterial disease, which precludes delivery of large-diameter transcatheter valve delivery systems
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Mario et al. (2019) conducted an observational in Transcatheter aortic valve replacement in patients with peripheral arterial disease. Intravascular Lithotripsy-Enabled Vascular Access was evaluated.
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