Key result
BMI over 29.3 linked to ~2.8-fold higher 1-year readmission risk after post-MI PCI.
Why the study?
Evidence regarding the relationship between body mass index and 1-year unplanned readmission was limited in patients with acute myocardial infarction after PCI.
Does body mass index predict 1-year unplanned readmission in Chinese patients with acute myocardial infarction after PCI?
Cohort (n=172)
No
Does body mass index predict 1-year unplanned readmission in Chinese patients with acute myocardial infarction after PCI?
In Chinese patients with AMI undergoing PCI, a BMI > 29.3 kg/m² is associated with a significantly increased risk of 1-year unplanned readmission, suggesting the obesity paradox does not apply to this specific population.
Answers are grounded in this paper and cite their sources.
BMI >29.3 kg/m² may flag higher readmission risk after AMI PCI; leaves open whether this challenges the obesity paradox or warrants targeted strategies.
Background . Evidence regarding the relationship between body mass index (BMI) and 1-year unplanned readmission was limited. Therefore, the objective of this research is to investigate whether BMI was independently related to 1-year unplanned readmission in Chinese patients with acute myocardial infarction (AMI) after percutaneous transluminal coronary intervention (PCI) after adjusting for other covariates. Methods . The present study was a cohort study. A total of 214 participants with AMI after PCI were involved in a hospital in China from 1 st January 2017 to 1 st January 2018. The target independent variable and the dependent variable were BMI measured at baseline and 1-year unplanned readmission, respectively. Covariates involved in this study included age, gender, TC, triglyceride, HDL-C, LDL-C, PT, APTT, INR, creatinine, HGB, LVEF, discharge medication, marital status, educational level, COPD, diabetes mellitus, heart failure, history of ischemic stroke, history of hemorrhagic stroke, arrhythmia, and hypertension. Results . The average age of 172 selected participants was 60.2 ± 10.8 years old, and about 68.6% of them was male. The rate of readmission in patients with AMI was 26.14%. The result of fully adjusted binary logistic regression showed BMI was negatively associated with risk of readmission after adjusting confounders (hazard ratio (HR) = 1.1, 95% CI 0.93–1.29). Nonlinear relationship was detected between BMI and 1-year unplanned readmission, whose point was 29.3. The effect sizes and the confidence intervals of the left and right sides of inflection point were 0.9 (0.7–1.2, P for nonlinearity = 0.530) and 2.8 (1.3–5.8, P for nonlinearity = 0.008), respectively. Conclusion . BMI has a nonlinear relationship with 1-year unplanned readmission in patients with myocardial infarction. The 1-year unplanned readmission rate of overweight patients (BMI > 29.3 kg/m 2 ) has increased significantly. Obesity paradox does not exist in terms of readmission of Chinese patients with myocardial infarction after PCI.
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Sun et al. (2020) conducted a cohort in Acute Myocardial Infarction (AMI) after percutaneous transluminal coronary intervention (PCI) (n=172). Body Mass Index (BMI) vs. Lower BMI (continuous baseline) was evaluated on 1-year unplanned readmission (HR 2.8, 95% CI 1.3-5.8, p=0.008). In Chinese patients with acute myocardial infarction after PCI, a BMI greater than 29.3 kg/m2 was associated with a increased risk of 1-year unplanned readmission.
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